- Drama: MR. BRAIN
- Romaji: MR. BRAIN
- Japanese: MR. BRAIN
- Director: Katsuo Fukuzawa, Yuichiro Hirakawa, Daisuke Yamamuro
- Writer: Mitsuharu Makita, Yoshiko Morishita
- Network: TBS
- Episodes: 8
- Release Date: May 23 – June 11, 2009
- Runtime: Saturday 20:00
- TV Ratings: 20.5%
- Language: Japanese
- Country: Japan
Plot
Takuya Kimura plays Ryusuke Tsukumo, a neurological scientist studying human nature at the Metropolitan Police Agency’s National Research Institute of Police Science. He tackles fundamental questions about human nature and overturns a few commonly-held beliefs along the way in a gripping mystery drama packed with plenty of emotional punch.
Ryusuke Tsukumo gets arrested himself for allegedly setting off an explosion. During his interrogation, he answers the questions using his keen sense of intellect and knack for deductive reasoning and turns the questions back on his interrogators, setting up inferences that point to a more likely suspect …
Cast
 |  |  |  |  |
| Takuya Kimura | Haruka Ayase | Hiro Mizushima | Sei Hiraizumi | Osamu Shitara |
| Ryusuke Tsukumo | Kazune Yuri | Toranosuke Hayashida | Junpei Funaki | Junichi Kanda |
 |  |  |  |  |
| Shigenori Yamazaki | Shunya Isaka | Yasufumi Hayashi | Katsuya Kobayashi | Yuji Tanaka |
| Koichi Ouchi | Katsumi Namikoshi | Kiyoshi Iwabuchi | Ippei Seta | Mitsuo Natsume |
 |  |  |  |  |
| Tortoise Matsumoto | Mao Daichi | Teruyuki Kagawa | Yukina Kinoshita | Shiho |
| Jotaro Nanba | Miharu Sasa | Tomomi Tanbara | cleaning lady | Mariko |
Additional Cast Members:
- Kiyotaka Tanaka
- Ebizo Ichikawa – Kohei Takei (ep1,7-8)
- Keiko Toda – host club customer (ep.1)
- Ryoko Hirosue – woman (ep.1)
- Yusuke Santamaria – Tsutomu Funada (ep.1)
- Masanobu Takashima – Kenzo Doi (ep.1)
- Kotaro Shiga – Goichi Tsuchida (ep.1)
- Kanji Tsuda – Kazuhiko Komine (ep.1)
- Ryohei Abe – yakuza (ep.1)
- Tomimasa Kikuguchi – detective (ep.1)
- Tetta Sugimoto – Hideki Kojima (ep1,3,7)
- Gackt – Teijiro Takegami (ep.2)
- Yosuke Kawamura – detective (ep.2,5)
- Yutaka Matsushige – Seiji Kishikawa (ep.2)
- Yasuto Kosuda – ep.2
- Sokyu Fujita – ep.2
- Hiroaki Fukui – Hidekazu Takada (ep.2)
- Satoshi Jinbo – Shusuke Tsumura (ep.2)
- Hideo Ishiguro – Kozo Sugiyama (ep.2)
- Yusuke Hirayama – Hideki Goto (ep.2)
- Koyuki – Kumiko Miyase (ep.2)
- Hiroyuki Onoue – crime lab member (ep2-3,5,7-8)
- Kazuya Kamenashi – Masakazu Wakui (ep.3)
- Saki Aibu – Megumi Goto (ep.3)
- Mantaro Koichi – Dr. Chihara (ep.3)
- Toru Shinagawa – Shinichi Hyuga (ep.3)
- Tatsuhito Okuda – Police commissioner (ep.3)
- Tae Kimura – Jun Nakagawa (ep.4-5)
- Takeru Satoh – Masaru Nakagawa (ep.4-5)
- Hideki Togi – Hitoshi Yagi (ep.4-5)
- Yuya Takayama – ep.4,5
- Yukie Nakama – Kanako Akiyoshi (ep.5-6)
- Shinji Rokkaku – Koichi Aoyama (ep5-6)
- Yujiro Komura – ep.5
- David Ito – Minoru Nishizaki (ep.5)
- Yo Yoshida – Ryoko Sakamoto (ep.5-6)
- Itsumi Osawa – Yuriko Matsushita (ep.5-6)
- Ken Mitsuishi – Yoshiyuki Aizawa (ep.7-8)
- Kazuma Suzuki – Shinichiro Ozaki (ep.7-8)
- Takeshi Obayashi – Yozo Kawase (ep.7)
- Takaya Kamikawa – Yosuke Kitazato (ep.7-8)
- Meikyo Yamada – ep.7,8
- Akira Hamada – Kohei Ozaki (ep.7-8)
- Tsuyoshi Hayashi – ep.7
- Shingo Katori – hijacker (ep.8)
